Adalat: A Comprehensive Overview

Characteristic	Details
Generic Name	Nifedipine
Dosage Forms	10 mg, 20 mg tablets
Route of Administration	Oral
Mechanism	Calcium Channel Blocker
Common Indications	Hypertension, Angina
Adverse Effects	Dizziness, Flushing
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Chemical Structure

The chemical structure of Adalat, known scientifically as Nifedipine, belongs to the class of dihydropyridine calcium channel blockers. It features a distinctive dihydropyridine ring, characterized by its molecular formula: C₁₇H₁₈N₂O₆. This structure underpins its pharmacological properties. The compound’s conformation facilitates interaction with L-type calcium channels, integral to its therapeutic effect. Key functional groups include the nitrobenzene moiety, pivotal in its action.

The presence of a methyl ester and a methoxycarbonyl group enhance its lipophilicity, optimizing membrane permeability. This structural aspect contributes to its efficacy in modulating vascular smooth muscle tone. As a result, Adalat effectively lowers blood pressure, providing relief in conditions like hypertension and angina.

Mechanism of Action

Adalat 10 mg operates as a potent calcium channel blocker. It exerts its effects by selectively inhibiting L-type calcium channels in vascular smooth muscle and cardiac tissue. This blockade leads to decreased intracellular calcium concentrations. Consequently, vascular smooth muscle relaxation ensues, resulting in vasodilation.

By dilating coronary and peripheral arteries, Adalat improves blood flow and reduces cardiac workload. This mechanism alleviates angina symptoms and lowers hypertension. Importantly, it acts without significantly affecting heart rate or conduction. Its action ensures cardiovascular efficiency without causing reflex tachycardia, a common side effect of other vasodilators.

Indications

Adalat 20 mg finds its primary indications in the management of hypertension and chronic stable angina. For hypertensive patients, it reduces systemic vascular resistance, achieving effective blood pressure control. This benefit extends to those with comorbid conditions, such as diabetes or renal impairment.

In angina, Adalat enhances myocardial oxygen supply while reducing oxygen demand. It proves beneficial for patients with exertional angina, providing symptomatic relief. Additionally, it serves as an adjunct therapy in vasospastic angina, where coronary artery spasm is prevalent.

Adalat Disposal

Proper disposal of Adalat is crucial to prevent environmental contamination and accidental ingestion. Expired or unused tablets should not enter household waste or sewage systems. Patients should return them to pharmacies with designated take-back programs.

If a pharmacy disposal program is unavailable, sealing Adalat in a plastic bag and mixing with undesirable substances like coffee grounds is recommended. This minimizes risk before placement in household trash. Ensuring responsible disposal protects ecosystems and public health.

Adverse Effects

Common adverse effects of Adalat include dizziness, flushing, and headache. These symptoms arise from its vasodilatory effects, often transient as the body adjusts. Peripheral edema may occur due to increased capillary permeability.

Serious reactions are rare but can include hypotension and arrhythmias. Caution is advised for patients with severe aortic stenosis or heart failure. Monitoring by healthcare professionals mitigates risk, ensuring therapeutic benefit outweighs potential harm.

Adalat for Sale Online

The digital marketplace offers Adalat with varying dosages. Buyers must exercise caution, verifying the legitimacy of sources. Licensed pharmacies assure quality and authenticity, safeguarding consumer health.

Consulting healthcare providers before purchasing online is vital. They offer guidance on suitable dosages and potential interactions. Adalat’s therapeutic value is best realized under professional supervision, ensuring safe and effective treatment outcomes.

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